People usually are getting care about the homepage SEO, and forgot about the other pages. When a webmaster is trying to get backlinks to his site, and he usually need to buy this backlinks for money, he always is putting the homepage url in the anchor text and forget to put also the inner pages when he make the second, third and other backlinks. That's why the inner pages has always lower PR than the homepages - just because 90% of the webmasters are not getting backlinks for their inner pages!
There is no difference in the optimization method for home page and inner page. But it is a good approach to start optimization for home page with primary keywords followed by inner pages with appropriate keywords
In my open-ion, Home pages always have more body weight because they are just that, the home page/index. These are listed by all robots first. Other web pages devote some time, you need to create sure you are connecting to them from the catalog and also developing off-site anchor bolts to these web pages. I.e. a particular content may be valuable if attached by another writer getting the details. Also more appropriate details is normally discovered on the website.